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KMID : 0931320140140010018
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2014 Volume.14 No. 1 p.18 ~ p.23
Complications and Management of Peptic Ulcer Disease
Bang Chang-Seok

Baik Gwang-Ho
Abstract
Despite the improvement of medical managements of peptic ulcer and decline of Helicobacter pylori infection, complications of peptic ulcer are still prevalent in clinical practice. This is because of the increased use of ulcerogenic medications such as aspirin or non-steroidal anti-inflammatory drug (NSAID) in elderly patients. Peptic ulcer complications include bleeding, perforation, pen-etration and gastric outlet obstruction. These complications need to be managed by multidisciplinary approaches such as combina-tion of endoscopic treatment, radiologic embolization, or surgical treatments. In addition to using proton pump inhibitors, H. pylorieradication and discontinuing ulcerogenic medications are essential in the prevention of recurrence. Although uncommon, non-H. pylori, non-NSAID ulcers should be suspected as a potential cause in recurrent cases of peptic ulcer complications.
KEYWORD
Peptic ulcer hemorrhage, Peptic ulcer perforation, Gastric outlet obstruction
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